A woman is dead after a crash on Highway 403 in Mississauga Wednesday night that also sent two construction workers to hospital.

The crash happened around 10 p.m. when a westbound car left the highway and hit a construction pickup truck on the shoulder of the road near Mavis Road.

The pickup truck then slammed into the back of a cube van.

The deceased woman was driving the car. Two men doing construction work on the highway who were in the back of the truck at the time were hurt — one of them critically.

Police are investigating.